Open Questions: Biomedical Diagnostic Technology

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Introduction

Gene chips

Microfluidics

Lab on a chip

DNA sequencing


Recommended references: Web sites

Recommended references: Magazine/journal articles

Recommended references: Books

Introduction



Recommended references: Web sites

Site indexes

Microarray links
Large categorized and annotated list of links. Part of a more general site on microarrays.

Sites with general resources

Publications by Rosetta Inpharmatics
Abstracts of published articles, mostly related to DNA microarrays.
Microarray resource
A resource page with a number of links to information about microarrays, provided by Ambion, Inc..

Surveys, overviews, tutorials

Microarrays
General information about microarray technology, from the NCBI Science Primer
Transistor Flow Control
October 2005 Scientific American In Focus article, subtitled "Forget valves--controlling fluids with electric fields."
The Incredible Shrinking Laboratory
August 1998 Science News article, about microfluidic "labs on a chip".


Recommended references: Magazine/journal articles

Speed reading
Philip Ball
Physics World, December 2010, pp. 24-28
Physicists may have the leading edge in the quest to sequence the human genome quickly and cheaply.
The Magic of Microarrays
Stephen H. Friend; Roland B. Stoughton
Scientific American, February 2002, pp. 44-49
DNA microarrays ("gene chips") can be used to detect specific genes or measure gene activity in tissues. They should eventually make it possible for physicians to provide truly personalized medicine.
Gene Chips and Functional Genomics
Hisham Hamadeh; Cynthia A. Afshari
American Scientist, November-December 2000, pp. 508-515
Microarrays make it possible to assess the genetic status of an organ or an entire organism. One application is understanding how environmental toxicants may affect gene expression.


Recommended references: Books


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