Open Questions: Diet, Metabolism, and Health
See also: Causes of aging --
The cardiovascular system --
Galaxy: Nutrition and Dietetics
- Categorized site directory. Entries usually include
Sites with general resources
Physicians Committee for Responsible Medicine
- Web site of "a nonprofit organization that promotes preventive
medicine, conducts clinical research, and encourages higher standards
for ethics and effectiveness in research." PCRM is an advocacy
organization which tends to oppose meat consumption,
health fads, and (supposedly) unhealthful
dietary habits promoted by fast food and agricultural industries.
It sponsors other sites, such as
The Cancer Project and
Atkins Diet Alert.
Surveys, overviews, tutorials
- Article from
Illnesses related to poor nutrition,
- Article from
High density lipoprotein,
Low density lipoprotein,
Is your brain making you fat?
- January 2010 article from
"We're getting fatter, but it's not all our fault,
says physiologist Professor Michael Cowley."
The Skinny on Trans Fatty Acids
- September 22, 2003 article from
Chemical & Engineering News describing the chemistry
of trans fatty acids and efforts to reduce their presence in
À Votre Santé
- July 2001 Scientific American News Scan article, subtitled
"Should Physicians Tell Some Nondrinkers To Start?"
Apple Juice: It Does a Heart Good
- February 2001 Scientific American news article about
antioxidants in apple juice and grape juice.
What's Good about Garlic and Eggs
- October 2000 Scientific American news article about
possible beneficial effects of garlic on cancer and eggs on
- A non-profit educational organization that promotes caloric
restricted diet. The site contains quite a bit of information,
as well as a
external links, and
There is also an
email discussion list.
Dr. Walford & Caloric Restriction
- Home page of Roy Walford, promoting caloric-restricted diets.
Contains some information,
but mostly promotes diet-related products.
- Article from
Some Non-Original Thoughts on Diet, Health, and Longevity
- Very good overview of diet, from the point of view of caloric
restriction for its potential longevity benefits, by Phil Graves.
Articles about Caloric Restriction with Adequate Nutrution
- The articles include an overview and personal experiences, by
The author also has some diet-related
articles about health and nutrition.
Why Eating Less Means Living Longer
- September 2000 article from
the relationship between longevity and genes for sirtuin
The Famine of Youth
- June 2000 Scientific American article by Gary Taubes,
subtitled "Severely restricting diet may increase life span, but
few will be able to follow such a harsh regimen."
120 year diet
- Transcript of April 2001 Australian TV show which presented
an interview with Roy Walford.
- Single-page overview of the appetite-stimulating hormone
North American Association for the Study of Obesity
- NAASO is a scientific organization for research on obesity.
The site includes
Association for the Study of Obesity
- British organization that promotes research on causes,
prevention, and treatment of obesity. The site
general information and
- Main page at MedlinePlus
dealing with obesity.
Includes external links of many types, such as news articles,
overviews, clinical trials, research, genetics, statistics,
and relevant organizations.
- Article from
Clinical Guidelines on the Identification, Evaluation, and
Treatment of Overweight and Obesity in Adults
- A report of the Obesity Education Initiative of the U. S.
National Institutes of Health.
Part of the
Understanding Adult Obesity
- A fact sheet on obesity for the general public, provided by
the U. S.
National Institute of Diabetes & Digestive & Kidney Diseases.
Making Fat-proof Mice
- November 2000 Scientific American news article about
how targeting a fat-protecting protein known as perilipin may
protect against obesity.
Fighting Fat with Protein
- October 2000 Scientific American news article about a
protein (uncoupling protein-1) that dissipates food energy instead
of allowing it to be stored as fat.
Virus boosts fat in chickens and mice
- August 2000 news article in Science News about research
that showed an adenovirus injected into chickens and mice seems to
result in additional body fat.
A switch that turns off fat
- August 2000 news article about how Wnt-10b blocks pre-fat
cells from becoming normal fat cells.
- April 1997 news article in Science News about the
finding of antibodies for an adenovirus in humans.
Viruses may leave a weighty legacy
- April 1997 news article in Science News about a report
that an infection by a virus can cause obesity as well as
cholesterol and triglyceride problems.
Mice crash diet secret
- July 2000 news article about an inhibitor of fatty acid
synthetase that decreases appetite in animals.
Scientists find 'fat thermostat' in brain
- September 1999 news article about how the hypothalamus
regulates body weight.
Atkins Diet Alert
- Web site sponsored by
Physicians Committee for Responsible Medicine. It promotes
a skeptical attitude towards the Atkins diet.
Low Carbohydrate Diets
- Transcript of an Australian radio interview with a
scientist who raises concerns about low carbohydrate diets.
Bypass's Big Boon
Science News, September 10, 2011
- Scientists spot key players in surgery's surprising
ability to reverse diabetes.
Hormones in Concert
The Scientist, December 2009
- Multiple hormones act in concert to regulate blood sugar
and food intake. The idea has already led to a new diabetes
therapy; will it also yield new strategies for obesity?
The Skinny Fat
The Scientist, January 2008
- What if you could make fat cells burn energy rather than
Scientific American, February 2007
Eat Your Way to Better DNA
The Scientist, September 2006
- Why what your grandmother ate while pregnant with your
mother might affect your children's health, and other findings
from the growing field of nutrigenomics.
Obesity: An Overblown Epidemic
W. Wayt Gibbs
Scientific American, June 2005, pp.
Science News, April 2, 2005
- Fattening revelations - and new mysteries - about the hunger
- Why Are We So Fat?
National Geographic, August 2004, pp. 46-61
- Article describes the problem of obesity in the U. S. and
elsewehre in the world. Causes (too much food, too little exercise) and
effects of obesity are explained.
Science News, February 28, 2004
- Unraveling the injurious biology of obesity.
Science News, February 8, 2003, pp 88-90
- There seems to be more confusion than ever in what the
best diet is for weight-control and general health -- low fat or
Rebuilding the Food Pyramid
Walter C. Willett; Meir J. Stampfer
Scientific American, January 2003, pp.
The Hunger Hormone?
Science News, February 16, 2002, pp. 107-108
- Researchers have long supposed some sort of chemical signal
controls the brain's sense of hunger. A hormone known as ghrelin
has emerged as a good candidate for this signal.
- Trans Fats
Science News, November 10, 2001, pp. 300-301
- Evidence is accumulating that trans fats, which contain
a type of unsaturated fatty acid, may be implicated in diseases
such as diabetes and coronary disease.
Science Week, November 3, 2001, pp. 282-284
- Choline is a nutrient which has long been recognized
as being essential, for instance, to avoid liver damage. It is
now thought to be helpful for brain development as well.
Science Week, April 14, 2001, pp. 238-239
- Proteins known as peroxisome proliferator activated receptors
(PPARs), and especially PPAR-γ,
act as molecular switches to control genes that regulate
fat intake. They may affect the development of diseases such as
cancer, diabetes, and heart disease.
- Caloric Restriction and Aging
Scientific American, January 1996, pp. 46-52
- Reduced caloric intake has been shown to increase longevity
in rodents and many other species. Whether the result is the same
for humans is still an open question.
Copyright © 2002 by Charles Daney, All Rights Reserved